| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2566592 | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2008 | 6 Pages |
Abstract
We have recently demonstrated that paradoxical sleep deprivation (PSD) potentiates the induction of amphetamine (AMPH)-induced behavioural sensitization by increasing its conditioned component. In the present study, the effects of sleep rebound (induced by 24 h recovery period from PSD) were studied on AMPH-induced behavioural sensitization. Sleep rebound attenuated the acute locomotor-stimulating effect of AMPH. AMPH-induced behavioural sensitization was context-specific and was also attenuated by sleep rebound. These results strengthen the notion that sleep conditions can influence AMPH-induced behavioural sensitization.
Keywords
Related Topics
Life Sciences
Neuroscience
Biological Psychiatry
Authors
Mariana Bendlin Calzavara, Monica Levy Andersen, Daniela Fukue Fukushiro, Giorgia Batlle Lopez, Vanessa Costhek Abílio, Sergio Tufik, Roberto Frussa-Filho,