| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2567101 | Pulmonary Pharmacology & Therapeutics | 2014 | 8 Pages |
Abstract
Our results suggest that asthma is associated with MKK3 over-expression in CD8+ cells. We have also demonstrated that MKK3 may be critical for airway neutrophilia, but not eosinophilia, suggesting that this may be a target worthy of further consideration in the context of diseases associated with neutrophil activation such as severe asthma and COPD.
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Authors
T. Holand, Y. Riffo-Vasquez, D. Spina, B. O'Connor, F. Woisin, C. Sand, M. Marber, K.B. Bacon, C. Rohlff, C.P. Page,