| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2567456 | Pulmonary Pharmacology & Therapeutics | 2008 | 5 Pages |
Abstract
These findings support the notion that IFN gamma may be one of the important mediators regulating angiogenetic balance in IPF. However, IFN gamma-1b decreases MIG levels, finding that in association with no alteration in IP-10 and I-TAC levels, could explain in part the nonbeneficial effect of this drug in IPF.
Keywords
HRCTmonokine induced by interferon-γCXC ligandCXC ReceptorENA-78ITACT helper 1Th1CXCRTLCOIP-10CXCLIL-8FEV1IFN-γIPFFVCCXC chemokinesMIGAngiostasisAngiogenesisinterferon-gammaInterleukin-8BALFELISAEnzyme-linked immunosorbent assayhigh-resolution computed tomographyForced expiratory volume in 1 sTreatmentdiffusing capacity for carbon monoxideforced vital capacityPartial pressure of oxygenidiopathic pulmonary fibrosisBronchoalveolar lavage fluidPathogenesis
Related Topics
Health Sciences
Medicine and Dentistry
Pulmonary and Respiratory Medicine
Authors
Katerina M. Antoniou, Nikolaos Tzanakis, Eleni G. Tzortzaki, Katerina Malagari, Anastassios V. Koutsopoulos, Michael Alexandrakis, Athol U. Wells, Nikolaos M. Siafakas,