Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2567472 | Pulmonary Pharmacology & Therapeutics | 2010 | 8 Pages |
Abstract
This study established a safe dose range and demonstrated the feasibility of prolonged, repeated dosing of pf-tPA. High doses (â¥1 mg/kg/d) were associated with pulmonary hemorrhage that may be due, in part, to accumulation of drug in the lungs.
Keywords
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Authors
Nicholas P. Lackowski, Josh E. Pitzer, Meghan Tobias, Zachary Van Rheen, Rajiv Nayar, Mitra Mosharaff, Kathleen A. Stringer,