Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2567504 | Pulmonary Pharmacology & Therapeutics | 2011 | 8 Pages |
Abstract
Additional to its human small airway relaxant effects we now demonstrate that capsazepine has potent anti-inflammatory effects on viral stimulus-induced cytokines in HBEC from healthy as well as asthmatic donors. Based on these data we suggest that exploration of structure-activity amongst the multifaceted capsazepinoids is warranted in search for compounds of therapeutic value in viral-induced, steroid-resistant asthma.
Keywords
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Authors
Angelica Brandelius, Yulyana Yudina, Jenny Calvén, Leif Bjermer, Morgan Andersson, Carl Persson, Lena Uller,