Article ID Journal Published Year Pages File Type
2567640 Pulmonary Pharmacology & Therapeutics 2008 6 Pages PDF
Abstract
Conclusion: LPS-induced lung inflammation is strongly inhibited by olprinone accompanying the enhancement of IL-10 and the inhibition of inflammatory cytokines. Results of the in vitro experiment suggest that alveolar macrophages may play an important role in ameliorating LPS-induced lung inflammation and the mechanism of its effect is different from that of steroid.
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Related Topics
Health Sciences Medicine and Dentistry Pulmonary and Respiratory Medicine
Preview
Pretreatment with olprinone hydrochloride, a phosphodiesterase III inhibitor, attenuates lipopolysaccharide-induced lung injury via an anti-inflammatory effect
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