| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2568888 | Toxicology and Applied Pharmacology | 2012 | 8 Pages |
Abstract
⺠Cisplatin induces acute renal failure (ARF). ⺠The expression of Oat1, Oat3 and Mrp2 were changed during ARF. ⺠The regulated expression of Oat1, Oat3 and Mrp2 is an adaptive protected response. ⺠JBP485 could facilitate the adaptive protective action.
Keywords
para-aminohippuratePAHMDAOat3Oat1JBP485qRT-PCRARFMrp2AUCRIPA bufferOatorganic anion transportersBUNSODindoxyl sulfateSuperoxide dismutasecisplatinmalondialdehydearea under the plasma concentration-time curveAcute renal failureNephrotoxicityblood urea nitrogenquantitative real time-polymerase chain reactionmultidrug resistance-associated protein 2
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Authors
Tao Liu, Qiang Meng, Changyuan Wang, Qi Liu, Xinjin Guo, Huijun Sun, Jinyong Peng, Xiaochi Ma, Taiichi Kaku, Kexin Liu,