| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2569140 | Toxicology and Applied Pharmacology | 2012 | 7 Pages |
Abstract
⺠Vehicle effects on sensitization potency were investigated in the LLNA. ⺠In vivo cutaneous absorption of contact sensitizers was visualized using TPM. ⺠Sensitizing potency of isothiocyanates depends on the presence of a phthalate. ⺠Phthalate induced cutaneous absorption via the pilosebaceous units. ⺠Vehicle-dependent reactivity regulates sensitization potency.
Keywords
ACDRBITCDibutylphthalateLLNALYVE-1PSUTPMDBPFITCPBSDMSOLocal lymph node assayContact allergyACD, Allergic contact dermatitisDimethylsulfoxideRhodamine B isothiocyanateMass spectrometryphosphate buffer salinefluorescein isothiocyanateTwo-photon microscopyPilosebaceous unitHPLClymphatic vessel endothelial hyaluronan receptor 1
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Authors
Carl Simonsson, Anna-Lena Stenfeldt, Ann-Therese Karlberg, Marica B. Ericson, Charlotte A.M. Jonsson,