Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2569180 | Toxicology and Applied Pharmacology | 2012 | 7 Pages |
Abstract
⺠200 mM 2-(chloroethyl) ethyl sulfide (CEES) induces mutations in mouse skin. ⺠This dose of CEES is not overtly toxic, as assayed by histopathology. ⺠2,6-Dithiopurine (DTP), applied after CEES-treatment, abolishes CEES-mutagenesis. ⺠This supports the idea that sulfur mustards exhibit long biological half-lives.
Keywords
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Authors
Stephen Boulware, Tammy Fields, Elizabeth McIvor, K. Leslie Powell, Erika L. Abel, Karen M. Vasquez, Michael C. MacLeod,