| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2569183 | Toxicology and Applied Pharmacology | 2012 | 8 Pages |
Abstract
⺠PPARα/γ ligand MCC-555 exhibits anti-proliferative activity in pancreatic cancer cells. ⺠MCC-555 affects KLF4 expression following by NAG-1 and p21 expression in a PPARγ independent manner. ⺠MCC-555 also affects cyclin D1 down-regulation in a PPARγ dependent manner. ⺠To our knowledge, this is the first report that MCC-555 affects anti-proliferative activity in pancreatic cancer cells, along with multiple targets.
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Authors
Kyung-Won Min, Xiaobo Zhang, Temjenmongla Imchen, Seung Joon Baek,