| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2569238 | Toxicology and Applied Pharmacology | 2011 | 8 Pages |
Abstract
⺠Arsenic impairs mitochondrial energy metabolism leading to neuronal apoptosis. ⺠Arsenic differentially affects mitochondrial complexes, I - III and IV being more sensitive than complex II. ⺠Arsenic-induced apoptosis initiates through ROS generation or impaired [Ca2+]i homeostasis. ⺠MiADMSA reverses arsenic toxicity via intracellular arsenic- chelation, antioxidant potential or both.
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Authors
Nidhi Dwivedi, Ashish Mehta, Abhishek Yadav, B.K. Binukumar, Kiran Dip Gill, Swaran J.S. Flora,