| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2569750 | Toxicology and Applied Pharmacology | 2011 | 7 Pages |
Abstract
⺠4-chlorotetrazolo[1,5-a]quinoxaline is a quinoxaline derivative. ⺠The effect of 4-chlorotetrazolo[1,5-a]quinoxaline on mast cells was investigated. ⺠4-chlorotetrazolo[1,5-a]quinoxaline reversibly inhibited Syk activation. ⺠4-chlorotetrazolo[1,5-a]quinoxaline could be useful for IgE-mediated allergy.
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![4-Chlorotetrazolo[1,5-a]quinoxaline inhibits activation of Syk kinase to suppress mast cells in vitro and mast cell-mediated passive cutaneous anaphylaxis in mice](/preview/png/2569750.png "First Page Preview: 4-Chlorotetrazolo[1,5-a]quinoxaline inhibits activation of Syk kinase to suppress mast cells in vitro and mast cell-mediated passive cutaneous anaphylaxis in mice")
Authors
Kui Lea Park, Na Young Ko, Jun Ho Lee, Do Kyun Kim, Hyuk Soon Kim, A-Ram Kim, Erk Her, Bokyung Kim, Hyung Sik Kim, Eun-Yi Moon, Young Mi Kim, Hang-Rae Kim, Wahn Soo Choi,