| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2573543 | Trends in Pharmacological Sciences | 2007 | 5 Pages |
Abstract
There is strong evidence for the existence of Gq/11-coupled dopamine receptors in the brain but the mechanism by which dopamine signaling activates Gq/11, or its roles in neuronal function, are only just beginning to be understood. The importance of such a pathway is underlined by putative links between dopamine-regulated phosphoinositide signaling and several central nervous system disorders that include schizophrenia, addiction and Parkinson's disease.
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Authors
Asim J. Rashid, Brian F. O’Dowd, Vaneeta Verma, Susan R. George,