| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2575689 | The American Journal of Geriatric Pharmacotherapy | 2012 | 12 Pages |
Abstract
The evidence-based literature compared with PIs is the most complete pharmacotherapy information source about both age-related clearance changes and pharmacokinetic DDIs with antidepressants. Future rigorously designed observational studies are needed to examine the combined risk of antidepressants with age-related decline in clearance and potential DDIs on important health outcomes such as falls and fractures in older patients.
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Authors
Richard D. PhD, Steven M. MD, PhD, Jordan F. MD, Joseph T. PharmD, MS,