Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2576665 | International Congress Series | 2007 | 4 Pages |
Abstract
We employed ACB to characterize Gastric Emptying Time (GET — T1/2) and Gastric Activity Contraction (GAC) in dogs after erythromycin administration. An erythromycin dose of 50 mg was infused, after 24 h of fasting. Without erythromycin administration, ACB recorded GET of 157.5 ± 13.6 min (mean ± SD) and GAC of 4.4 ± 0.5 cpm (cycles per minute). After erythromycin administration was measured a GET of 84.2 ± 19.7 min. GAC was measured before, during and after erythromycin administration and results were, respectively, 4.4 ± 0.5, 4.9 ± 0.6 and 4.2 ± 0.3 cpm. Erythromycin produced efficient prokinetic action in gastric emptying and increased gastric motility in dogs.
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Authors
U. Andreis, L.A. Corá, M.F. Américo, R.B. Oliveira, O. Baffa, J.R.A. Miranda,