Genomic imprinting in Turner syndrome

The selective silencing of certain alleles depending on the parent of origin is known as genomic imprinting. Specific cognitive skills, statural growth and visceral adiposity have all been linked to the parental origin of the single normal X-chromosome in girls and women with Turner syndrome (TS). The putatively imprinted traits in TS reflect typical differences between eukaryotic males and females. This chapter reviews the evidence for parental X-chromosome imprinting in the TS phenotype.