Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2578310 | Revista del Laboratorio Clínico | 2012 | 15 Pages |
Abstract
The implementation of equations for estimating glomerular filtration rate (GFR) in clinical laboratory reports has placed the spotlight on the limitations of creatinine measurements and has promoted the establishment of an international program for standardisation. We have analysed the current state of implementation of this program with regard to traceability, commutability, imprecision, systematic error, as well as information on the type of equation to use and reference values, as well as the creatinine reagents commonly used in Spanish laboratories. Most of the measurement procedures have traceability to the reference method, and meet the requirements of imprecision. The available information available on the inaccuracy, the total error of measurement, verification of the commutability of calibration materials used, the glomerular filtration equation to use, and reference values in the paediatric population is unsatisfactory or non-existent in most commercial firms evaluated.
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Authors
Maria José Diez-De-Los-RÃos Carrasco, Rosario Montañés Bermúdez, SÃlvia Grà cia Garcia,