Article ID Journal Published Year Pages File Type
2578399 Revista del Laboratorio Clínico 2011 13 Pages PDF
Abstract
Glomerular filtration is the best index for assessing renal function. Despite being subjected to several sources of variability, serum creatinine is the most common glomerular filtration marker in use. Cystatin C is a low molecular weight protein which is more sensitive than creatinine, particularly for the identification of initial small decreases in renal function. The use of cystatin C in certain groups of patients such as elderly, children or diabetics appears to provide more information than creatinine. However, serum cystatin C can be influenced by non-renal factors. Currently, there is not enough scientific evidence to recommend the use of cystatin C to assess renal function instead of creatinine and creatinine equations.
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Life Sciences Biochemistry, Genetics and Molecular Biology Clinical Biochemistry
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