| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2581369 | Chemico-Biological Interactions | 2009 | 7 Pages |
Abstract
Moxidectin is identified as a BCRP substrate since its Bcrp1-mediated secretion into breast milk and the involvement of Bcrp1 in intestinal and bile secretion has been demonstrated. This interaction has pharmacokinetic and toxicological consequences. The most important toxicological consequences of the interaction between BCRP and moxidectin may be related with the presence of drug residues in milk.
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Authors
Miriam Perez, Alba G. Blazquez, Rebeca Real, Gracia Mendoza, Julio G. Prieto, Gracia Merino, Ana I. Alvarez,