| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2582912 | Environmental Toxicology and Pharmacology | 2015 | 6 Pages |
Abstract
- Cyclophosphamide is known to cause severe cardiac toxicity.
- N-acetylcysteine (NAC) is an antioxidant with free radical scavenging activity.
- CP increased the serum cardiac enzymes, ADMA, TNF-α and decreased the NOx.
- NAC pretreatment protects against CP-induced cardiotoxicity.
- NAC inhibits oxidative and nitrosative stress induced by CP.
Related Topics
Life Sciences
Environmental Science
Health, Toxicology and Mutagenesis
Authors
Heba H. Mansour, Shereen M. El kiki, Hesham F. Hasan,