Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2583212 | Environmental Toxicology and Pharmacology | 2012 | 6 Pages |
Abstract
⺠The impaired disposition of probe drugs is due to both liver and kidney dysfunctions in CCl4-model rats. ⺠We examine the effect of CCl4 on the mRNA expression and activity of SULT1A1 and UGT1A6. ⺠We examine the effect of CCl4 on the pharmacokinetics of phenacetin and acetaminophen.
Related Topics
Life Sciences
Environmental Science
Health, Toxicology and Mutagenesis
Authors
Yan Zhang, Yanyan Jia, Mengmeng Yang, Peng Yang, Yun Tian, Aiping Xiao, Aidong Wen,