Article ID Journal Published Year Pages File Type
2583212 Environmental Toxicology and Pharmacology 2012 6 Pages PDF
Abstract
► The impaired disposition of probe drugs is due to both liver and kidney dysfunctions in CCl4-model rats. ► We examine the effect of CCl4 on the mRNA expression and activity of SULT1A1 and UGT1A6. ► We examine the effect of CCl4 on the pharmacokinetics of phenacetin and acetaminophen.
Keywords
Related Topics
Life Sciences Environmental Science Health, Toxicology and Mutagenesis
Preview
The impaired disposition of probe drugs is due to both liver and kidney dysfunctions in CCl4-model rats
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