Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2584251 | Environmental Toxicology and Pharmacology | 2009 | 6 Pages |
Abstract
In the present study, two antioxidant components (polysaccharopeptide complex P1âa and condensed tannin P1âb) from rose (Rosa rugosa) flowers were each incubated with mouse erythrocytes to investigate their effect on erythrocyte superoxide dismutase (SOD), and catalase (CAT) activities. It was found that the activities of Cu, Zn-SOD and CAT were markedly increased after incubation for 3 h with rose flower fractions at the concentration of 500 μg/ml. Similar changes were also observed in the erythrocyte gene expression of SOD and CAT. These results show that P1âa and P1âb are effective antioxidants that increase the activity and the gene expression of SOD and CAT in mouse erythrocytes.
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Authors
Y. Jiang, J.H. Wong, Z.F. Pi, T.B. Ng, C.R. Wang, J. Hou, R.R. Chen, H.J. Niu, F. Liu,