| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2589806 | NeuroToxicology | 2013 | 12 Pages |
Abstract
⺠Salsolinol, a neurotoxin implicated in Parkinson's disease was found to exhibit profound effect on NSCs. ⺠NSCs undergo substantial morphological changes, cytotoxicity and functional impairment on exposure to salsolinol. ⺠Molecular mechanism showed activation of apoptosis/impairment of PI3K/Akt survival signaling. ⺠SAL mediated toxicity was counteracted on multiple neurotrophin support.
Related Topics
Life Sciences
Environmental Science
Health, Toxicology and Mutagenesis
Authors
A. Shukla, T.M. Mohapatra, A.K. Agrawal, D. Parmar, K. Seth,