Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2591076 | Neurotoxicology and Teratology | 2012 | 4 Pages |
Abstract
⺠Toluene is a volatile organic compound (VOC) and a ubiquitous air pollutant. ⺠Acute effects have been characterized however several possible modes of action exist. ⺠Acute inhalation of toluene produced transcriptional effects in rat brain 18 h. ⺠This study examined whether these acute effects are evident after sub-chronic exposure. ⺠Based on these data, long-term gene expression changes cannot be predicted by acute responses.
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Authors
Susan D. Hester, Andrew F.M. Johnstone, William K. Boyes, Philip J. Bushnell, Timothy J. Shafer,