Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2592310 | Regulatory Toxicology and Pharmacology | 2013 | 20 Pages |
Abstract
- We developed statistical models to predict toxicity of untested substances.
- Models are described for 4 repeat-dose and 3 developmental endpoints.
- Models use only petroleum compositional data and basic biometric data.
- The correlations between the observed and model-predicted values are high.
- Model results show good agreement with observed BMD10 measures.
Keywords
Related Topics
Life Sciences
Environmental Science
Health, Toxicology and Mutagenesis
Authors
Mark J. Nicolich, Barry J. Simpson, F. Jay Murray, Randy N. Roth, Thomas M. Gray,