| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2592321 | Regulatory Toxicology and Pharmacology | 2011 | 6 Pages |
Abstract
⺠Field matched fume condensate from oxidized Type III built up roofing asphalt was tested for tumor initiation and promotion. ⺠After 6 months of study, evidence of tumor initiation, but not tumor promotion was observed in mouse skin. ⺠These results suggest a mechanism of action that includes genotoxicity. ⺠Compared to polycyclic aromatic hydrocarbons, field-matched fume has a relatively weak potency.
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Authors
James J. Freeman, Ceinwen A. Schreiner, S. Beazley, Donald M. Burnett, Charles R. Clark, Suneeta Mahagaokar, Craig M. Parker, Christopher W. Stewart, Mark S. Swanson, Earl W. Arp,