| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2592657 | Regulatory Toxicology and Pharmacology | 2009 | 8 Pages |
Abstract
The results of the study indicate that the major obstacles are a lack of certified reference materials (CRMs) and the direction of resources towards the development of new instrument-based methods rather than towards the refinement of the existing pre-column HPLC method for regulatory use. To move away from the mouse bioassay, Canada should invest in: basic research to develop a complete set of CRMs for PSP toxins; method refinement to increase sample throughput; and exercises to gain international acceptance of the pre-column HPLC method.
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Authors
Allison L. Guy, Gilly Griffin,