Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2593882 | Reproductive Toxicology | 2012 | 7 Pages |
Abstract
⺠Pregnant rats were treated with artesunate, mefloquine and their association. ⺠Artesunate induced embryolethality and bones malformations. ⺠Mefloquine induced maternal toxicity with no fetus anomalies. ⺠The artesunate/mefloquine combination resulted in a reduced developmental toxicity.
Keywords
Related Topics
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Environmental Science
Health, Toxicology and Mutagenesis
Authors
Ana Cláudia Boareto, Juliane Centeno Müller, Samanta Luiza de Araujo, Ana Carolina Lourenço, Emerson Luiz Botelho Lourenço, Caroline Gomes, Bruna Minatovicz, Natália Lombardi, Francisco Roma Paumgartten, Paulo Roberto Dalsenter,