| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2595677 | Toxicology | 2012 | 11 Pages |
Abstract
⺠Different concentrations of arsenite cause biphasic effects in HaCaT cells. ⺠p53-survivin signal pathway plays a role in arsenite-induced biphasic effects. ⺠ERKs inactivate p53, but improve survivin expression by NF-κB/mot-2. ⺠JNKs block survivin expression by preventing p53 from mdm2-mediated degradation. ⺠ERKs and JNKs play roles in arsenite-induced biphasic effects.
Keywords
Related Topics
Life Sciences
Environmental Science
Health, Toxicology and Mutagenesis
Authors
Yuan Li, Rongrong Jiang, Yue Zhao, Yuan Xu, Min Ling, Ying Pang, Lu Shen, Yun Zhou, Jianping Zhang, Jianwei Zhou, Xinru Wang, Qizhan Liu,