Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2600487 | Toxicology Letters | 2010 | 6 Pages |
Abstract
In summary, the novel androgen-sensitive yeast assays have a large potential for various applications, e.g. as pre-screening in doping analysis or cattle feeding. A combination of both assays, exploiting these two phylogenetic very different yeasts, allows detection of the activity of a wide range of androgenic substances.
Keywords
DHTPGKWADASARMERES. cerevisiaeeGFPhERαandrogen responsive element8-prenylnaringenin8-PNS. pombeHAR1DMSOEsr1androgensWorld Anti-Doping AgencyDopingDihydrotestosteroneDimethyl sulfoxideAnti-androgensEstrogen responsive elementphosphoglycerate kinaseSelective androgen receptor modulatorAREpolymerase chain reactionPCRgreen fluorescent proteinHuman androgen receptor genehigh performance liquid chromatographyHPLCGas chromatographyhuman estrogen receptor α
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Authors
Sylvi Wolf, Felicitas Rataj, Oliver Zierau, Kai Ostermann, Patrick Diel, Maria Kristina Parr, Günter Vollmer, Gerhard Rödel,