Article ID Journal Published Year Pages File Type
2601300 Toxicology Letters 2008 6 Pages PDF
Abstract

The distinction between carcinogens with DNA-reactive and epigenetic modes of action and the application of mode-of-action considerations to risk assessment is reviewed. A bioindicator-based risk assessment strategy is described. This approach involves the use of mechanistic data to establish a “toxicologically insignificant daily intake”.

Related Topics
Life Sciences Environmental Science Health, Toxicology and Mutagenesis
Authors
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