Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2601300 | Toxicology Letters | 2008 | 6 Pages |
Abstract
The distinction between carcinogens with DNA-reactive and epigenetic modes of action and the application of mode-of-action considerations to risk assessment is reviewed. A bioindicator-based risk assessment strategy is described. This approach involves the use of mechanistic data to establish a “toxicologically insignificant daily intake”.
Keywords
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Authors
Gary M. Williams,