Syndrome de Brugada

Brugada syndrome is a rare genetic disease. Since its first description in 1992, epidemiological specificities, pathophysiologic mechanisms and overall comprehension of the disease have much improved. A careful follow-up of cohorts of patients with the syndrome have allowed a better recognition of risk factors for severe complications (sudden death), and an appraisal of the actual prognosis of the disease. In this manuscript, we sought to provide the reader with a concise and didactic review on the Brugada syndrome. Beside the report of current knowledge of the disease, we will also discuss areas of uncertainty, most notably regarding therapeutic management.