Article ID Journal Published Year Pages File Type
2628741 Complementary Therapies in Clinical Practice 2015 7 Pages PDF
Abstract

ObjectiveTo evaluate the efficacy of Malva sylvestris L. flowers extract for treatment of FC.MethodAdults with FC were allocated to receive the M. sylvestris L. flowers aqueous extract syrup (MSL, 1 g extract/day) or placebo for four weeks. Frequency of constipation symptoms and stool forms were assessed every week. Self-reported improvement was assessed after treatment.ResultsCompared with placebo, more increase was observed in defecation frequency (F = 18.8, P < 0.001) and more decrease was observed in frequency of all constipation symptoms by MSL (F = 16.5 to 25.3, all P values <0.001). Also, the MSL group experienced more reduction in frequency of hard stool forms (45.4% vs. 9.1%, P < 0.001) and reported more improvement in all symptoms (all P values <0.01) than placebo.ConclusionThe M. sylvestris L. flowers aqueous extract is efficacious and safe for the treatment of FC in adult patients. Investigating the mechanisms of action is warranted. IRCT2014031617032N1.

Related Topics
Health Sciences Medicine and Dentistry Complementary and Alternative Medicine
Authors
, , , , , , , , ,