Reliability and validity of the Chinese version of the PedsQL Multidimensional Fatigue Scale in children with acute leukemia

BackgroundThe PedsQL Multidimensional Fatigue Scale (PedsQL™ MFS) is widely used to rate fatigue in children living in English-speaking countries. However, insufficient instruments are available to conduct parallel assessment on fatigue in parents and children in China. In this regard, an appropriate measurement method must be developed.ObjectivesThis study aims to determine the reliability and validity of the Chinese-language PedsQL™ MFS.MethodsChildren with cancer (n = 125) and their parents were surveyed in Guangzhou, China. The parents of children aged 2–4 years completed the PedsQL™ MFS proxy reports, whereas the other children and their parents completed the questionnaires by themselves.ResultsThe PedsQL™ MFS-Chinese version demonstrated satisfactory internal consistency reliability (child self-report Cronbach's α = 0.87; parent self-report Cronbach's α = 0.93). The factor loadings of the items ranged from 0.78 to 0.87 for general fatigue, 0.56–0.78 for sleep/rest fatigue, and 0.62–0.89 for cognitive fatigue.ConclusionThis study proves that the PedsQL™ MFS-Chinese version is an effective tool for screening fatigue in Chinese children with cancer.