An Efficacious and Cost-Effective Pharmacologic Treatment for Helicobacter pylori

Helicobacter pylori (H. pylori) is a common widespread infection that, if left untreated, is a risk factor for gastric cancer. H. pylori is a contagious disease with a high prevalence in low socioeconomic areas. The multidrug regimen for eradication of H. pylori can be difficult to complete because of medication side effects, confusing dosing regimens, and cost. This article reviews H. pylori infection pathophysiology, symptoms, screening, and diagnosis. Using the most recent evidence-based research, recommendations have been made to achieve the most efficacious and cost-effective treatment of H. pylori in the primary care setting.