Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2661044 | The Journal for Nurse Practitioners | 2012 | 5 Pages |
Abstract
Naloxone is an opioid antagonist that competitively binds to opioid receptors and reverses all of their effects. The indication for use is respiratory depression as a result of known or suspected opioid overdose. Clinicians involved in patient care must use the drug appropriately, rather than as a diagnostic tool, such as to determine the etiology of a change in mental status. This article reviews the pharmacokinetics and pharmacodynamics of naloxone. In addition, the appropriate administration is reviewed using a case study approach.
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Authors
Erin M. McMenamin,