Links Between Infectious Diseases and Cardiovascular Disease: A Growing Body of Evidence

It is widely acknowledged that a systemic inflammatory process is involved in atherogenesis leading to subsequent cardiovascular disease (CVD). Several types of microbes have been implicated as possible causative agents in acquired CVD. This article reviews current and emerging links established between specific microorganisms and cardiac vessel and other vascular damage. Studies are reviewed that have investigated a possible role for antibiotics in treatment and prevention; other potential primary and secondary preventive measures are then explored. Nurse practitioners have an important role in recognizing and effectively managing the multiple complex processes involved in the development of CVD.