A Comparison Between Postoperative Nausea and Vomiting in General Anesthesia With Isoflurane-Remifentanil or Isoflurane in Cholecystectomy Laparoscopic Patients

PurposeThe purpose of the study was to compare postoperative nausea and vomiting (PONV) between laparoscopic cholecystectomy patients under general anesthesia with isoflurane and remifentanil-isoflurane.DesignAn observational study was used.MethodsThis observational study was performed on 102 patients who were candidates for laparoscopic cholecystectomy under anesthesia with isoflurane or remifentanil-isoflurane. The patients were evaluated for PONV in the PACU and 3 and 6 hours after the operation. Data were analyzed with descriptive and analytical statistics.FindingsAt the time of recovery, the incidence of nausea and vomiting was less in patients under general anesthesia with isoflurane when compared to general anesthesia with remifentanil-isoflurane (P < .04). Nausea and vomiting was also less in the isoflurane group (2%) versus the remifentanil-isoflurane group (9%) at 3 and 6 hours after surgery, but the difference was not significant.ConclusionsThe incidence of PONV in cholecystectomy laparoscopic patients under combined remifentanil with isoflurane anesthesia was relatively low, and it was a bit less in patients under isoflurane anesthesia alone.