Managing large-volume literature searches in research synthesis studies

BackgroundSystematic reviews typically require searching for, retrieving, and screening a large volume of literature, yet little guidance is available on how to manage this volume.PurposeWe detail methods used to search for and manage the yield of relevant citations for a mixed-methods, mixed research synthesis study focused on the intersection between family life and childhood chronic physical conditions.MethodsWe designed inclusive search strings and searched nine bibliographic databases to identify relevant research regardless of methodological origin. We customized searches to individual databases, developed work-arounds for transferring large volumes of citations and eliminating duplicate citations using reference management software, and used this software as a portal to select citations for inclusion or exclusion. We identified 67,555 citations, retrieved and screened 3,617 reports, and selected 800 reports for inclusion.Discussion/ConclusionsSystematic reviews require search procedures to allow consistent and comprehensive approaches and the ability to work around technical obstacles.