Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2696678 | Archives des Maladies Professionnelles et de l'Environnement | 2007 | 8 Pages |
Abstract
For the effects with toxic effect threshold, the extrapolation consists in applying an uncertainty factor from 1 to 10; for the effects without threshold, the approach is based on a quantitative extrapolation by mathematical modelling, for an intake at the lower end of the dose-response curve. Many committees offer HTVs in data base on the internet. France has recently initiated a process for the development of her own HTVs.
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Authors
F. Dor, N. Bonvallot,