Safety and efficacy of overnight orthokeratology in myopic children

BackgroundThis prospective case series was conducted to describe the safety and efficacy of orthokeratology with the Emerald™ Contact Lens for Overnight Orthokeratology (Oprifocon A; Euclid Systems Corporation, Herndon, Virginia) among young myopes.MethodsTwenty subjects (ages 10 to 16) were enrolled in the 6-month pilot study. Subjects were fit empirically with overnight orthokeratology lenses and evaluated at 1 day, 1 week, 1 month, 2 months, 3 months, and 6 months.ResultsSixteen subjects completed the study. The mean baseline spherical equivalent refraction (SER) was −2.06 diopters (D) (±0.75). The mean SER at 6 months was −0.16 D (±0.38). The mean baseline uncorrected acuity was 0.78 (±0.28) logarithmic minimum angle of resolution (logMAR) equivalent (20/100 Snellen). The mean logMAR equivalent at 6 months was −0.03 ± 0.12 (<20/20 Snellen). On average, 40% of eyes showed some type of corneal staining between the 1-week and 6-month visits. No serious adverse events occurred during the study.ConclusionsIn contrast to previously published studies that reported maximum results at 2 weeks, subjects reached maximum reduction in myopia at the 1-week visit and, on average, obtained a 92.2% reduction in spherical equivalent refractive error at 6 months. This pilot study lends to a growing body of evidence that short-term correction of mild to moderate myopia with overnight orthokeratology is safe and efficacious in children and adolescents.