| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2703259 | Journal of the American College of Clinical Wound Specialists | 2012 | 9 Pages |
Abstract
Our data demonstrates that HA has the potential to normalize keloid fibroblast characteristic features such as hyperproliferation, growth factor production and ECM deposition depending on the specific genotype of the keloid fibroblast cell line. This study suggests that high molecular weight HA can be used to replenish HA deposition in keloid fibroblasts thereby decreasing fibrosis and ultimately decreasing keloid manifestation.
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Authors
Andrea PhD, Jessica Lynn MD, Mackenzie MS, Richard MD, FACS, FACCWS,