Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2706229 | PM&R | 2011 | 29 Pages |
Abstract
Pregabalin is established as effective and should be offered for relief of PDN (Level A). Venlafaxine, duloxetine, amitriptyline, gabapentin, valproate, opioids (morphine sulphate, tramadol, and oxycodone controlled-release), and capsaicin are probably effective and should be considered for treatment of PDN (Level B). Other treatments have less robust evidence or the evidence is negative. Effective treatments for PDN are available, but many have side effects that limit their usefulness, and few studies have sufficient information on treatment effects on function and QOL.
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Authors
Vera MD, FRCP(C), John MD, FAAN, Gary M. MD, MPH, FAAN, Miroslav MD, Jeffrey MD, FAAN, David MD, Eva MD, PhD, FAAN, Donald J. MD, FAAN, Bruce MD, FRCP(C), MPH, James W. MD, MS, FRPC, Douglas MD,