| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2707460 | PM&R | 2012 | 6 Pages |
ObjectiveTo compare physical activity levels and dietary choices of patients who have chronic hepatitis C (CHC) with those of blood donors (BDs).DesignA prospective survey.SettingA liver disease treatment center and a blood donor center from a nonprofit health system.PatientsA total of 149 subjects (93 with CHC and 56 BDs) participated. Subjects were 18 years or older and agreed to participate; those with CHC had no evidence of cirrhosis.MethodsAll subjects provided basic clinical information and completed a nutrition survey, which contained questions about dietary choices and their frequency, and the Human Activity Profile, which measured maximum effort (Maximum Activity Score; MAS) and daily activity (Adjusted Activity Score; AAS).Main Outcomes MeasurementsMAS and AAS scales and 13 indices on the nutrition survey. Independent samples t-tests, Pearson correlations, and multiple stepwise regression analyses were performed.ResultsNo significant differences were found between BDs and patients with CHC in terms of age, gender, race, body mass index, hyperlipidemia, hypertension, or diabetes mellitus. Mean body mass index was 27.5, 17.8% had hyperlipidemia, and 9.6% had diabetes. BDs reported significantly more exercise per week (mean: patients with CHC = 193.6 minutes/week and BDs = 280.4 minutes/week; P = .039) and had a significantly greater MAS (mean: patients with CHC = 77.2 and BDs = 87.4, P = .0001) and AAS (mean: patients with CHC = 72.58 and BDs = 83.8, P = .0001). Stepwise multiple regression analysis proposed 2 models predicting AAS: the presence of CHC (R = .445; R2 = .198; adjusted R2 = .184); and the presence of CHC and presence of hypertension (R = .537; R2 = .289; adjusted R2 = .263). BDs consumed significantly more alcohol and starchy foods than did patients with CHC (P = .0001 and P = .031, respectively), which may be explained by the compliance of patients with CHC to their hepatologist's recommendations regarding the minimization of alcohol consumption.ConclusionsPersons with CHC participate in less activity and less vigorous physical activity than do BDs and consume less starch and alcohol. These data about activity level and dietary intake in patients with CHC are novel; few data on these topics have been published previously. Low level of activity adds a substantial risk to this overweight CHC population, many of whom have multiple components of metabolic syndrome.
