Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2724810 | Journal of Pain and Symptom Management | 2007 | 14 Pages |
Abstract
The recent recognition of the magnitude of cardiovascular risk of both nonselective nonsteroidal anti-inflammatory drugs and COX-2 selective inhibitors, in addition to the persistent concerns about the use of opioids, has brought increased attention to nonsystemic, topical analgesics. These agents have a favorable safety profile and there is increasing evidence indicating their efficacy for a variety of pain disorders. The use of topical analgesics in the treatment of the most prevalent musculoskeletal pain syndromes is described, with a focus on mechanisms for drug delivery and clinical trials data.
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Authors
Steven P. Stanos,