Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2724811 | Journal of Pain and Symptom Management | 2007 | 9 Pages |
Abstract
Because of their localized activity and low systemic absorption, topical analgesics have a favorable safety profile and a low risk for drug-drug interactions. There is a growing body of evidence on the efficacy and safety of these agents in a variety of pain disorders, including the most prevalent neuropathic pain conditions. The molecular basis for the usage of peripheral analgesics in neuropathic pain and the available clinical trial evidence for a wide variety of topical agents are reviewed.
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Authors
Oscar A. de Leon-Casasola,