Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2730228 | Journal of Pain and Symptom Management | 2011 | 8 Pages |
Abstract
The topical application of an MTD-PLO gel in doses <45Â mg/day did not result in trough MTD serum concentrations associated with analgesia. An observer placebo response may explain the perceived benefit of MTD applied topically as a PLO gel in doses <45Â mg/day. The evaluation of systemic absorption of MTD-PLO gel in doses >45Â mg/day is warranted.
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Authors
Robert K. PharmD, Caroline RN, John MD, Preston MD, Alan PharmD,