Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2736160 | Journal of Pain and Symptom Management | 2012 | 11 Pages |
Abstract
Adverse drug reactions are common and associated with substantial economic and human costs. Particularly among older adult populations, preventable adverse drug reactions are often caused by drug-drug interactions. All analgesics have side effect profiles and many have known drug-drug interactions. Opioids are recognized as a necessary option for managing moderate-to-severe pain, yet many opioid side effects can be enhanced by metabolic interactions within the liver, involving other drugs, diseases, or genetics.
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Authors
Jeffrey Gudin,