Additive Effects of Numbness and Muscle Aches on Fatigue Occurrence in Individuals with HIV/AIDS Who Are Taking Antiretroviral Therapy

These findings are consistent with physiological research and provide evidence that analyzing multiple symptom change over time can provide a more accurate representation of an individual's symptom experience. When evaluating patients with muscle aches or numbness, particularly when both symptoms are present, an evaluation of fatigue should be considered. Similarly, if fatigue is reported, underlying physiological assessments for neuropathic symptoms and muscle aches may be considered.