Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2737830 | Seminars in Radiation Oncology | 2016 | 7 Pages |
Abstract
Preoperative short-course radiotherapy and preoperative long-course chemoradiotherapy are the standards of care for high-risk rectal cancer in different parts of the world. Both treatments are effective in local control and carry a low morbidity. The advantage of short course is its simplicity, whereas long course has the advantage of downsizing tumors thus increasing the chance of sphincter preservation. Although 2 randomized trials comparing short course and long course have been performed, the better form of preoperative treatment remains a subject of discussion. This article reviews the evidence supporting each approach, and it discusses their relative merits and future directions.
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Authors
Samuel Y. Ngan,